DERIVADOS DE 2 PIRROLIDONA COMO AGONISTAS DE PROSTANOIDES

摘要

This invention relates to 8-aza prostanoid analogs which are generally EP4 receptor agonists and are represented by Formula I:wherein Q, B, X, J, Z, A and R<1>-R<6 >are as defined, their synthesis and use for treatment of osteoporosis and increasing bone density.