发明名称 Isolated tissue protein PP18
摘要 A protein PP18 is isolated having the following characteristics: (a) an electrophoretic mobility in the region of that of beta 1-globulins; (b) an isoelectric point between 5.6 and 6.2; (c) a sedimentation coefficient s20,w of 5.0+/-0.2 S; (d) a molecular weight determined in an ultracentrifuge of 82,300+/-5,600; (e) a carbohydrate fraction of 2.3+/-1.3 g/100 g (mannose 0.15+/-0.1, xylose 0.5+/-0.5, galactose 0.5+/-0.2, glucose 0.2+/-0.1, N-acetylglucosamine 0.7+/-0.2, and N-acetylneuraminic acid 0.25+/-0.2, each g/100 g). Also described is the amino acid composition of the protein and a process for its isolation. Antiserum is prepared and used in an immunoassay to detect the protein.
申请公布号 US4746731(A) 申请公布日期 1988.05.24
申请号 US19850735060 申请日期 1985.05.17
申请人 BEHRINGWERKE AKTIENGESELLSCHAFT 发明人 BOHN, HANS;WINCKLER, WILHELM
分类号 A61K35/50;A61K38/16;C07K14/47;C07K16/18;G01N33/50;G01N33/68;(IPC1-7):C07K3/00;C07K15/00;C07K15/06;C07K15/14 主分类号 A61K35/50
代理机构 代理人
主权项
地址