发明名称 |
ORAL FORMULATION OF ANHYDROUS OLANZAPINE FORM I |
摘要 |
<p>The invention relates to a solid formulation for the oral administration of olanzapine that comprises a core of anhydrous olanzapine Form I or a pharmaceutically acceptable salt thereof and, optionally, pharmaceutically acceptable excipients, said core being coated with a functional polymer that acts as filmogenic agent. The method for obtaining it comprises: i) providing anhydrous olanzapine Form I or a salt thereof and, optionally, pharmaceutically acceptable excipients in solid form; ii) providing a functional polymer that acts as filmogenic agent; iii) preparing a dispersion of said functional polymer in an aqueous medium,-and applying the dispersion obtained in step iii) onto the solid form of step i).</p> |
申请公布号 |
EP1965773(A1) |
申请公布日期 |
2008.09.10 |
申请号 |
EP20060841451 |
申请日期 |
2006.12.19 |
申请人 |
LABORATORIOS LESVI, S. L. |
发明人 |
DIEZ MARTIN, IGNACIO;UBEDA PEREZ, CARMEN;PABLO ALBA, PABLO |
分类号 |
A61K9/32;A61K31/551 |
主分类号 |
A61K9/32 |
代理机构 |
|
代理人 |
|
主权项 |
|
地址 |
|