发明名称 |
INDUCTION OF TUMOR IMMUNITY BY VARIANTS OF FOLATE BINDING PROTEIN |
摘要 |
The present invention is directed to variants of antigens comprising folate binding protein epitopes as a composition associated with providing immunity against a tumor in an individual. The variant is effective in inducing cytotoxic T-lymphocytes but preferably not to the extent that they become sensitive to silencing by elimination, such as by apoptosis, or by anergy, as in unresponsiveness. |
申请公布号 |
US2015175658(A1) |
申请公布日期 |
2015.06.25 |
申请号 |
US201414339797 |
申请日期 |
2014.07.24 |
申请人 |
Board of Regents, The University of Texas System ;The Henry M. Jackson Foundation for the Advancement of Military Medicine, Inc. |
发明人 |
IOANNIDES Constantin G.;PEOPLES George E. |
分类号 |
C07K7/06;A61K39/00 |
主分类号 |
C07K7/06 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
Austin TX US |