发明名称 |
DNA VACCINE COMPOSITIONS AND METHODS OF USE |
摘要 |
<p>The present invention is directed to a DNA vaccine for immunization against HIV. The invention comprises a DNA molecule that has a sequence encoding a plurality of viral proteins capable of stimulating an immune response against HIV. The DNA molecule is rendered safe for use as a vaccine by the disruption of genes encoding reverse transcriptase, integrase, and Vif. The DNA molecule is further rendered safe by at least a partial deletion of the 3' LTR.</p> |
申请公布号 |
CA2538840(C) |
申请公布日期 |
2014.02.18 |
申请号 |
CA20042538840 |
申请日期 |
2004.09.16 |
申请人 |
UNIVERSITY OF KANSAS MEDICAL CENTER |
发明人 |
NARAYAN, OPENDRA;LIU, ZHENQIAN |
分类号 |
A61K39/21;A01N43/04;A01N63/00;A61K;A61K39/00;A61K48/00;A61P31/18;C07H21/04;C12N15/00;C12N15/49;C12N15/63;C12N15/85;C12N15/86 |
主分类号 |
A61K39/21 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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