发明名称 |
STABILIZED LIPID FORMULATION OF APOPTOSIS PROMOTER |
摘要 |
596047 Disclosed herein is an orally deliverable pharmaceutical composition comprising a Bcl-2 family protein inhibitory compound, e.g., ABT-263, a heavier-chalcogen antioxidant and a substantially non-aqueous lipid carrier, wherein said compound and said antioxidant are in solution in the carrier. The composition is suitable for oral administration to a subject in need thereof for treatment of a disease characterized by overexpression of one or more anti-apoptotic Bcl-2 family proteins, for example cancer. |
申请公布号 |
NZ596047(A) |
申请公布日期 |
2013.11.29 |
申请号 |
NZ20100596047 |
申请日期 |
2010.04.30 |
申请人 |
ABBVIE INC. |
发明人 |
HAIGHT, ANTHONY R;SANZGIRI, YESHWANT;ZHOU, DELIANG;SCHMITT, ERIC;ZHANG, GEOFF;CATRON, NATHANIEL;TONG, PING;FICKES, MICHAEL;HEEMSTRA, KATHERINE;FISCHER, CRISTINA |
分类号 |
A61K9/00;A61K9/48;A61K31/5377;A61K47/00;A61K47/02;A61K47/14;A61K47/20;A61P35/00 |
主分类号 |
A61K9/00 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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