PROTEIN COATED BIOACTIVE SUTURE FOR CELL TRANSPLANTATION AND METHOD FOR PRODUCING THEREOF

摘要

The invention concerns a suture coated with albumin (an albumin-coated suture) for use in introducing cells seeded thereon into a soft tissue of a patient. The suture of the invention advantageously comprises cells seeded thereon. The suture of the invention is advantageously coated with human serum albumin. The cells seeded on the suture of the invention are advantageously non-embryonic stem cells. The present invention further concerns a method for coating a surgical suture with albumin comprising incubating said suture in an albumin containing aqueous solution. The invention further provides a method for seeding cells onto an albumin-coated suture comprising incubating an albumin-coated suture in a cell culture comprised in a liquid cell culture medium. The invention further provides a method for using an albumin-coated suture for introducing cells seeded thereon into a soft tissue of a patient. The invention further concerns a method for introducing cells into a soft tissue of a patient comprising introducing an albumin-coated suture into said soft tissue of said patient, wherein said albumin-coated suture comprises said cells to be introduced seeded thereon.