发明名称 |
HUMAN ANTIBODIES TO HUMAN RANKL |
摘要 |
Isolated human antibodies or antigen-binding fragments thereof, which specifically bind to human RANKL and block hRANKL binding to a RANK receptor, are provided. The antibodies are useful in preventing or treating disorders and/or diseases, which are associated with RANKL/RANK interactions, including bone disorders or cancer. |
申请公布号 |
US2012114665(A1) |
申请公布日期 |
2012.05.10 |
申请号 |
US200913059851 |
申请日期 |
2009.08.19 |
申请人 |
MARTIN JOEL H.;ECONOMIDES ARIS N.;RAZ REGINA;REGENERON PHARMACEUTICALS, INC. |
发明人 |
MARTIN JOEL H.;ECONOMIDES ARIS N.;RAZ REGINA |
分类号 |
A61K39/395;A61P19/08;A61P35/00;C07K16/18;C12N15/13;C12N15/63;C12P21/02 |
主分类号 |
A61K39/395 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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