发明名称 |
METHOD FOR TREATING KIDNEY DISORDERS |
摘要 |
The present invention relates to a method for treating, delaying and/or preventing renal dysfunction/failure in a mammal comprising administering a therapeutically effective amount of a substance capable of inducing and/or enhancing Pax2 expression. Furthermore, the invention relates to the use of an effective dose of a substance capable of inducing and/or enhancing Pax2 expression in a mammal for the preparation of a pharmaceutical composition for treating, preventing or delaying a renal dysfunction/failure in a mammal. Additionally, the present invention provides for a method for converting mesenchymal tissue into an epithelial tissue comprising the administration of an effective amount of a substance capable of inducing and/or enhancing Pax2 expression in said mesenchym and for a method for the regeneration of renal stemcells comprising the administration of an effective amount of a substance capable of inducing and/or enhancing Pax2 expression.
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申请公布号 |
US2010055786(A1) |
申请公布日期 |
2010.03.04 |
申请号 |
US20090572583 |
申请日期 |
2009.10.02 |
申请人 |
ROTHENPIELER UWE WALDEMAR;IMGRUND MICHAEL CARL ELMAR |
发明人 |
ROTHENPIELER UWE WALDEMAR;IMGRUND MICHAEL CARL ELMAR |
分类号 |
C12N5/074;A61K33/00;A61K38/17;A61K38/18;A61K38/19 |
主分类号 |
C12N5/074 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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