摘要 |
A composition comprising 8-(tosylamino)quinoline is provided to inhibit production of nitric oxide, growth of cancer cells and C6 glioma cell, production of PGE2(prostaglandin 2), and activity of IKK(I kappa B alpha kinase) and Src kinase, thereby preventing or treating inflammatory diseases, immune diseases or tumors. The composition for preventing or treating inflammatory diseases, immune diseases or tumors comprises 8-(tosylamino)quinoline or pharmaceutically acceptable salts thereof including an acid addition salt selected from hydrochloric acid, hydrobromic acid, phosphonic acid, sulfuric acid, tartaric acid, acetic acid, citric acid, malic acid, methanesulphonic acid and gluconic acid.
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申请人 |
KNU-INDUSTRY COOPERATION FOUNDATION |
发明人 |
CHO, JAE YOUL;LEE, YONG GYU;LEE, JI YEON;BYEON, SEE UN;KIM, JOO YOUNG;KIM, BYUNG HUN |