发明名称 A FUNGICIDALLY ACTIVE COMPOUND
摘要 A DNA construct comprising a DNA sequence encoding an antifungal polypeptide, which sequence comprises the nucleotide sequence shown in SEQ ID No. 1 or an analogue thereof, which i) hybridizes with a DNA sequence comprising the nucleotide sequence shown in SEQ ID No. 1, or with a probe hybridizing with the nucleotide sequence SEQ ID No. 1, ii) encodes a polypeptide which reacts with an antibody reactive with at least one epitope of the polypeptide having the amino acid sequence shown in SEQ ID No. 2, and/or iii) encodes a polypeptide having the amino acid sequence shown in the appended SEQ ID No. 2 or a sequence homologous thereto, provided that the DNA sequence is different from one which encodes the polypeptide having the amino acid sequence shown in SEQ ID No. 2 except for an asparagine in position 4, an alanine in position 24, a lysine in position 32, a phenylalanine in position 42 and a tyrosine in position 50. The antifungal polypeptide encoded by the DNA construct may be used for combating or controlling fungal infections, in particular on plants.
申请公布号 CA2139837(A1) 申请公布日期 1994.01.20
申请号 CA19932139837 申请日期 1993.07.09
申请人 NOVO NORDISK AS 发明人 PEDERSON ANDERS H;HALKIER TORBEN;NIELSEN BIRTE A;LANGE LENE;MIKKELSEN JAN M;RASMUSSEN GRETHE;HANSEN MOGENS T
分类号 C12N15/09;A01N37/46;A01N63/00;A01N63/04;A61K38/00;A61P31/04;A61P31/10;C07H21/04;C07K14/37;C07K14/38;C12N1/15;C12N15/31;C12P21/02;C12R1/66;C12R1/69;(IPC1-7):C12N15/31;A61K38/16;C12N1/19;C12N1/21 主分类号 C12N15/09
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