摘要 |
A DNA construct comprising a DNA sequence encoding an antifungal polypeptide, which sequence comprises the nucleotide sequence shown in SEQ ID No. 1 or an analogue thereof, which i) hybridizes with a DNA sequence comprising the nucleotide sequence shown in SEQ ID No. 1, or with a probe hybridizing with the nucleotide sequence SEQ ID No. 1, ii) encodes a polypeptide which reacts with an antibody reactive with at least one epitope of the polypeptide having the amino acid sequence shown in SEQ ID No. 2, and/or iii) encodes a polypeptide having the amino acid sequence shown in the appended SEQ ID No. 2 or a sequence homologous thereto, provided that the DNA sequence is different from one which encodes the polypeptide having the amino acid sequence shown in SEQ ID No. 2 except for an asparagine in position 4, an alanine in position 24, a lysine in position 32, a phenylalanine in position 42 and a tyrosine in position 50. The antifungal polypeptide encoded by the DNA construct may be used for combating or controlling fungal infections, in particular on plants.
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