发明名称 |
MODIFIED BORDETELLA ADENYLATE CYCLASE COMPRISING OR LACKING CD11B/CD18 INTERACTION DOMAIN AND USES THEREOF |
摘要 |
The invention relates to modified Bordetella adenylate cyclase toxins which are deficient for CD11b/CD18 binding and to their use in the preparation of pharmaceutical composition for the treatment of whooping cough and/or for the protection against Bordetella infection. The invention also relates to specific fragments of Bordetella adenylate cyclase comprising the CD11b/CD18 interaction domain and their use, especially for targeting a molecule of interest to CD11b expressing cells.
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申请公布号 |
KR20060034645(A) |
申请公布日期 |
2006.04.24 |
申请号 |
KR20057024407 |
申请日期 |
2005.12.19 |
申请人 |
INSTITUT PASTEUR;CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (CNRS) |
发明人 |
LECLERC CLAUDE;EL AZAMI EL IDRISSI MOHAMMED;LADANT DANIEL;BAUCHE CECILE;SEBO PETER;LOUCKA JIRINA;OSICKA RADIM |
分类号 |
C07K14/235;A61K39/00;A61K39/10;A61P11/00;A61P31/00;C12N9/88;C12N15/60 |
主分类号 |
C07K14/235 |
代理机构 |
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主权项 |
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地址 |
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