| 发明名称 |
SOLUTION PREPARATION CONTAINING ANTIBODY AT HIGH CONCENTRATION |
| 摘要 |
Disclosed is a stable antibody-containing liquid formulation comprising 40 to 1000 mM arginine and 10 to 200mM methionine. Further disclosed is a method for inhibiting dimerization of molecules of an antibody in a liquid formulation containing the antibody, comprising adding arginine and methionine to the liquid formulation. |
| 申请公布号 |
NZ586378(A) |
申请公布日期 |
2012.06.29 |
| 申请号 |
NZ20080586378 |
申请日期 |
2008.12.26 |
| 申请人 |
CHUGAI SEIYAKU KABUSHIKI KAISHA;F. HOFFMANN-LA ROCHE AG |
发明人 |
MORICHIKA, TOSHIYUKI;KAMEOKA, DAISUKE;IMAEDA, YOSHIMI;MAEDA, TERUTOSHI;STAUCH, OLIVER BORIS |
| 分类号 |
A61K39/395;A61K9/08;A61K47/18;A61P43/00 |
主分类号 |
A61K39/395 |
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