INTEGRATED MICROFLUIDIC AND SOLID STATE PYROSEQUENCING SYSTEMS
摘要
The invention provides for sequencing a nucleic acid molecule based on the detection of base incorporation by the release of pyrophosphate (PPi) using a new enzyme system comprising adenosine diphosphate (ADP)-glucose pyrophosphorylase (AGPase) and its substrate ADP-glucose.
申请公布号
WO2011102808(A1)
申请公布日期
2011.08.25
申请号
WO2011SG00070
申请日期
2011.02.21
申请人
AGENCY FOR SCIENCE, TECHNOLOGY AND RESEARCH;GOEL, SANKET;GONG, MIN;RAHMAN, ABDUR RUB ABDUR;FOO, SHIHUI