发明名称 |
COMPOSITION AND METHOD FOR TREATMENT OF TUMORS WITH UDPG |
摘要 |
UDPG shows tumor-specific inhibition of PRPP and this suggests that this action might prove to be useful in combination therapy with inhibitors of purine and pyrimidine nucleotide systhesis in various rescue regimens. High levels of PRPP in tumors were greatly affected by treatment with UDPG. UDPG can be used in treatment in conjuction with other anti-tumor drugs such as methotrexate, 6-mercaptopurine, 5-fluorouracil or 2,6-dimercaptopurine. |
申请公布号 |
ZA8509740(B) |
申请公布日期 |
1986.07.30 |
申请号 |
ZA19850009740 |
申请日期 |
1985.12.20 |
申请人 |
MEMORIAL HOSPITAL FOR CANCER AND ALLIED DISEASES |
发明人 |
EARL BALIS |
分类号 |
C02F1/44;A61K;A61K31/505;A61K31/52;A61K31/565;A61K31/675;A61K31/70;A61K31/7042;A61K31/7052;A61K31/7064;A61K31/7072;A61P35/00;C07C;C07D;C07H19/10 |
主分类号 |
C02F1/44 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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