发明名称 |
IMPROVED THERMAL UNIFORMITY FOR THERMAL CYCLER INSTRUMENTATION USING DYNAMIC CONTROL |
摘要 |
A method for performing polymerase chain reactions (PCR) for improving thermal non-uniformity is provided. The method includes measuring a first temperature, by a first sensor, of a first sample block sector of a sample block and measuring a second temperature, by a second sensor, of a second sample block sector of the sample block that is adjacent to the first sample block sector. The method further includes calculating, by a thermoelectric controller, a difference in temperature between the first temperature and the second temperature and adjusting, by the thermoelectric controller, the first temperature of the first sample block sector based on the difference in temperature by using one or more thermoelectric coolers. The one or more thermoelectric coolers is configured to heat or cool the first sample block sector by adjusting power output from the thermoelectric controller. |
申请公布号 |
EP2556173(A2) |
申请公布日期 |
2013.02.13 |
申请号 |
EP20110766806 |
申请日期 |
2011.04.08 |
申请人 |
LIFE TECHNOLOGIES CORPORATION |
发明人 |
CONNER, THOMAS A.;LIM, CHEE KIONG;PALLAS, MICHAEL C.;CHING, CHEE WEE |
分类号 |
C12Q1/68;B01L3/00;B01L7/00;C12M1/38;G01N33/50 |
主分类号 |
C12Q1/68 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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