COMPOSITIONS AND METHODS FOR INHIBITION OF OR TREATMENT OF DENGUE VIRUS INFECTION
摘要
The present invention relates to a method of interfering with dengue infection comprising interfering with dengue virus binding to a syndecan present on a cell targeted by dengue virus. The present invention further relates to treating a patient for dengue virus infection comprising administering to a patient, either having a dengue infection or a patient exposed to dengue infection, an effective amount of an agent that interferes with dengue virus binding to a syndecan on a surface of a cell targeted by dengue virus. The present invention further relates to a pharmaceutical composition comprising a pharmaceutically acceptable carrier, and an effective amount of an agent that interferes with dengue virus binding to a syndecan on a surface of a cell targeted by dengue virus.
申请公布号
WO2011153458(A3)
申请公布日期
2012.01.26
申请号
WO2011US39107
申请日期
2011.06.03
申请人
UNIVERSITY OF ROCHESTER;AREVALO, MARIA T.;SIMPSON-HAIDARIS, PATRICIA J.;JIN, XIA;CHEN, HUIYUAN;QUINN, MATTHEW H.
发明人
AREVALO, MARIA T.;SIMPSON-HAIDARIS, PATRICIA J.;JIN, XIA;CHEN, HUIYUAN;QUINN, MATTHEW H.